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Matrix metalloproteinases (MMPs) are a family of proteolytic zinc-containing enzymes involved in physiological as well as in pathological processes in the human organism. MMPs play a key role in the remodeling of the extracellular matrix. Such a process may occur because of tissue homeostasis, morphogenesis, and tissue repair. However, remodeling could also be a part of many pathological states such as arthritis, cardiovascular diseases, neurodegenerative diseases, or impaired development in congenital anomalies. This book overviews the role of MMPs in different pathologies affecting the human body.
Metalloproteinases. --- Metalloproteases --- Metalloenzymes --- Proteinase --- Life Sciences --- Human Genetics --- Molecular Genetics --- Genetics and Molecular Biology --- Biochemistry
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Biomaterials are often designed to act as scaffolds, i.e., 3D porous templates that support and stimulate the growth of healthy tissue and then safely dissolve once they have performed their functions. This book provides a picture of the current state of the art in the field of scaffolds for tissue engineering, highlighting the potential associated to the latest scientific and technological advancements. The former part of the book focuses on the repair of ""hard"" tissues (primarily bone) by means of bioceramic/glass scaffolds, and the latter deals with the applications of polymeric scaffolds for regenerating ""soft"" tissues and structures including the peripheral nerve, heart, gastric mucosa and pancreas. Special emphasis is given to the challenges associated to scaffold manufacturing, biomimetic properties and cell-scaffold interactions.
Tissue engineering. --- Biomedical engineering --- Regenerative medicine --- Tissue culture --- Physical Sciences --- Engineering and Technology --- Materials Science --- Biomaterials --- Tissue Engineering
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This book discusses canine and feline skin cytology and the importance of this diagnostic tool in interpreting skin lesions. With more than 600 clinical and cytological color pictures, it explains the cytological patterns observed in all cutaneous inflammatory and neoplastic lesions in cats and dogs, as well as cutaneous metastasis of non-primary skin neoplasms. The first part of the book describes cell morphology and cytological patterns, providing an overview of the normal structure of the skin. In the second chapter, readers learn how to choose the best techniques for different types of lesions. Further chapters present the cytological findings in the main inflammatory and neoplastic skin diseases. By focusing on the macroscopic aspects of the lesions from which the cells are collected, it helps readers to interpret cytological specimens. The final chapter explores the cytology of cutaneous metastasis from internal organs or accessory glands. This book offers veterinary students and practitioners alike an essential diagnostic tool. .
Medicine. --- Dermatology. --- Pathology. --- Animal anatomy. --- Medicine & Public Health. --- Veterinary Medicine/Veterinary Science. --- Animal Anatomy / Morphology / Histology. --- Animal anatomy --- Animals --- Disease (Pathology) --- Clinical sciences --- Medical profession --- Anatomy --- Veterinary medicine. --- Morphology (Animals). --- Farriery --- Large animal medicine --- Large animal veterinary medicine --- Livestock medicine --- Veterinary science --- Medicine --- Animal health --- Domestic animals --- Livestock --- Animal morphology --- Body form in animals --- Zoology --- Morphology --- Medical sciences --- Diseases --- Medicine, Preventive --- Skin --- Losses --- Health Workforce --- Biology --- Physiology
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This book offers a comprehensive review of our current understanding of the planetary boundary layer, particularly the turbulent exchanges of momentum, heat and passive scalars between the surface of the Earth and the atmosphere. It presents and discusses the observations and the theory of the turbulent boundary layer, both for homogeneous and more realistic heterogeneous surface conditions, as well as the dispersion of tracers. Lastly it addresses the main problems arising due to turbulence in weather, climate and atmospheric composition numerical models. Written for postgraduate and advanced undergraduate-level students and atmospheric researchers, it is also of interest to anyone wanting to understand the findings and obtain an update on problems that have yet to be solved.
Physics. --- Meteorology. --- Atmospheric sciences. --- Fluids. --- Geophysics. --- Environmental sciences. --- Geophysics and Environmental Physics. --- Atmospheric Sciences. --- Environmental Physics. --- Numerical and Computational Physics, Simulation. --- Fluid- and Aerodynamics. --- Atmospheric turbulence. --- Turbulent boundary layer. --- Boundary layer --- Turbulence --- Atmospheric circulation --- Physical geography. --- Geography --- Hydraulics --- Mechanics --- Physics --- Hydrostatics --- Permeability --- Natural philosophy --- Philosophy, Natural --- Physical sciences --- Dynamics --- Aerology --- Atmospheric science --- Environmental science --- Science --- Atmospheric sciences --- Earth sciences --- Atmosphere --- Geological physics --- Terrestrial physics
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Artificial Intelligence is a huge breakthrough technology that is changing our world. It requires some degrees of technical skills to be developed and understood, so in this book we are going to first of all define AI and categorize it with a non-technical language. We will explain how we reached this phase and what historically happened to artificial intelligence in the last century. Recent advancements in machine learning, neuroscience, and artificial intelligence technology will be addressed, and new business models introduced for and by artificial intelligence research will be analyzed. Finally, we will describe the investment landscape, through the quite comprehensive study of almost 14,000 AI companies and we will discuss important features and characteristics of both AI investors as well as investments. This is the “Internet of Thinks” era. AI is revolutionizing the world we live in. It is augmenting the human experiences, and it targets to amplify human intelligence in a future not so distant from today. Although AI can change our lives, it comes also with some responsibilities. We need to start thinking about how to properly design an AI engine for specific purposes, as well as how to control it (and perhaps switch it off if needed). And above all, we need to start trusting our technology, and its ability to reach an effective and smart decision. .
Engineering. --- Data mining. --- Artificial intelligence. --- Computational intelligence. --- Computational Intelligence. --- Artificial Intelligence (incl. Robotics). --- Data Mining and Knowledge Discovery. --- Big Data. --- AI (Artificial intelligence) --- Artificial thinking --- Electronic brains --- Intellectronics --- Intelligence, Artificial --- Intelligent machines --- Machine intelligence --- Thinking, Artificial --- Bionics --- Cognitive science --- Digital computer simulation --- Electronic data processing --- Logic machines --- Machine theory --- Self-organizing systems --- Simulation methods --- Fifth generation computers --- Neural computers --- Construction --- Industrial arts --- Technology --- Intelligence, Computational --- Artificial intelligence --- Soft computing --- Algorithmic knowledge discovery --- Factual data analysis --- KDD (Information retrieval) --- Knowledge discovery in data --- Knowledge discovery in databases --- Mining, Data --- Database searching --- Big data. --- Artificial Intelligence. --- Data sets, Large --- Large data sets --- Data sets
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I Progymnasmata sono manuali usati nelle scuole antiche per il primo livello di istruzione retorica. Essi raccolgono una serie graduata di esercizi di composizione su tipologie testuali considerate fondamentali per l'acquisizione di abilità nella comunicazione. Il percorso impegna gli studenti nella produzione autonoma di testi e prevede la lettura di modelli classici e l'applicazione di precisi schemi di elaborazione. Per queste caratteristiche i Progymnasmata si presentano come un corso di studi completo per la formazione letteraria e culturale dei giovani. Il volume riordina la dottrina retorica trasmessa dalle fonti antiche (i quattro manuali in lingua greca, le più scarne testimonianze latine, i prontuari di esercizi fittizi, la documentazione papiracea, i commenti bizantini) organizzando la materia intorno alle principali voci tecniche. La sintesi è attenta a fornire un quadro esaustivo delle numerose fattispecie retoriche sia rispetto all'evoluzione della teoria sia mediante il confronto con la precettistica delle Artes. Sarà evidente il contributo specifico che i Progymnasmata hanno dato alla definizione di molti procedimenti retorici e al successo della formazione umanistica. *** Die Progymnasmata sind Handbücher, die in den antiken Schulen für das Erklimmen der ersten Stufe des Rhetorikunterrichts gebraucht wurden. Sie bestehen aus einer Serie nach Schwierigkeitsgrad gestaffelter Übungen zu verschiedenen Textarten, die als grundlegend für den Erwerb von Kommunikationskompetenzen galten. Das Training sieht das Verfassen von Texten vor, indem die Schüler klassische Vorbilder studieren und diese durch den Gebrauch gezielter Schemata bearbeiten. Aufgrund dieser Charakteristika erweisen sich die Progymnasmata als ein Gesamtwerk für die literarische und kulturelle Bildung der Jugend. Der vorliegende Band nimmt sich der lexikalischen Neuordnung der durch antike Quellen überlieferten Rhetoriklehre an. Aufgegriffen werden die vier Handbücher in grieschischer Sprache, die spärlichen lateinischen Zeugnisse, Sammlungen fiktiver Übungen, die Papyrusdokumentation und die byzantinischen Kommentare. Das Werk setzt sich zum Ziel, eine ausführliche Übersicht über die zahlreichen rhetorischen Figuren zu liefern, sowohl bezüglich der Entwicklung der Theorie, als auch im Hinblick auf die Vorschriften der Artes. Ersichtlich wird der Beitrag, den die Progymnasmata nicht nur zur Gestaltung zahlreicher Rhetorikverfahren, sondern auch insgesamt zur Entwicklung der humanistischen Bildung geleistet haben.
(Produktform)Paperback / softback --- Kommunikation --- Progymnasmata --- Rhetorik --- Rhetoriklehrbuch --- Rhetoriklehre --- (VLB-WN)1567: Hardcover, Softcover / Sprachwissenschaft, Literaturwissenschaft/Klassische Sprachwissenschaft, Literaturwissenschaft --- Rhétorique antique --- Rhetoric, Ancient. --- Greek language --- Composition and exercises --- Early works to 1800. --- Rhetoric, Ancient --- Grec (Langue) --- Rhétorique ancienne --- Glossaries, vocabularies, etc. --- Glossaires, vocabulaires, etc --- Ouvrages avant 1800 --- Composition et exercices --- Composition and exercises. --- Rhétorique ancienne --- Rhétorique antique. --- Greek language - Composition and exercises - Early works to 1800.
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This book constitutes the refereed proceedings of the 24th International Static Analysis Symposium, SAS 2017, held in New York, NY, USA, in August/September 2017. The 22 papers presented in this volume were carefully reviewed and selected from 50 submissions. The papers cover various aspects of the presentation of theoretical, practical, and applicational advances in area of static analysis that is recognized as a fundamental tool for program verification, bug detection, compiler organization, program understanding, and software maintenance. .
Computer science. --- Software engineering. --- Programming languages (Electronic computers). --- Computer logic. --- Mathematical logic. --- Computer Science. --- Logics and Meanings of Programs. --- Software Engineering. --- Programming Languages, Compilers, Interpreters. --- Mathematical Logic and Formal Languages. --- Algebra of logic --- Logic, Universal --- Mathematical logic --- Symbolic and mathematical logic --- Symbolic logic --- Computer science logic --- Computer languages --- Computer program languages --- Computer programming languages --- Machine language --- Computer software engineering --- Informatics --- Mathematics --- Algebra, Abstract --- Metamathematics --- Set theory --- Syllogism --- Logic, Symbolic and mathematical --- Electronic data processing --- Languages, Artificial --- Engineering --- Science --- Logic design. --- Design, Logic --- Design of logic systems --- Digital electronics --- Electronic circuit design --- Logic circuits --- Machine theory --- Switching theory --- Software engineering
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This technically oriented book on medicine as applied to extreme sports offers broad coverage of the field extending well beyond the usual focus on major trauma and acute injuries. In addition to the injuries and diseases associated with individual extreme sports, this book also addresses the topics of psychology, dermatology, ophthalmology, infectious diseases, physiology, nutrition, training, injury prevention strategies, rehabilitation, doping, treatment in hostile environments, and legal aspects. Innovative and less frequently considered topics are also discussed, such as recent advances in protective equipment and materials, the effects of exposure on whole-body vibration, and cold exposure risk management. More than 60 of the most authoritative experts from across the world have contributed to this book, drawing on their personal experiences and including practical examples whenever relevant. Both subject matter and illustrations have been selected with the utmost care, the latter including photographs of world-class athletes.The book’s multidisciplinary approach to the subject ensures that it will be relevant to a wide readership.
Extreme sports --- Action sports (Extreme sports) --- Medicine. --- Orthopedics. --- Sports medicine. --- Medicine & Public Health. --- Sports Medicine. --- Social aspects. --- Sports --- Orthopaedics --- Orthopedia --- Surgery --- Athletic medicine --- Athletics --- Medicine and sports --- Physical education and training --- Medicine --- Sports sciences --- Medical aspects
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